Stopnaus inj

INTRODUCTION

Stopnaus inj contains Ondansetron which belongs to a group of medicines called anti-emetics, which help to stop feeling or being sick. It is indicated to prevent and treat nausea and vomiting induced by cytotoxic therapy and radiotherapy and postoperative nausea and vomiting. This medicine works by blocking the action of serotonin levels in the brain which causes nausea and vomiting during chemotherapy or any other surgery.

Cytotoxic chemotherapy triggers the release of serotonin from the enterochromaffin cells of the small intestine. The released serotonin stimulates the vagal afferents through the 5-HT3 receptors and initiate the vomiting reflex. Ondansetron is a selective 5-HT3 receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Before receiving Stopnaus inj, tell your doctor if you have liver, kidney, or heart problems, pregnant women and breastfeeding mothers. Your doctor will administer the right dose depending on your child’s age and body weight. The common side effects are headache, constipation and dizziness.

USES OF Stopnaus inj

• Cancer chemotherapy-induced nausea and vomiting
• Postoperative nausea and/or vomiting

HOW Stopnaus inj WORKS

Stopnaus inj is a selective 5-HT3-receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. It works by blocking serotonin in the brain which causes nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

DIRECTIONS FOR USE

Stopnaus inj should be only given by a doctor or nurse. Your healthcare provider will administer an intravenous injection (into a vein) or, after dilution, an intravenous infusion.

SIDE EFFECTS OF Stopnaus inj

COMMON

• Headache
• A sensation of flushing and warmth
• Constipation
• Pain, redness, burning at the injection site

RARE

• Dizziness during rapid intravenous administration
• Skin rash
• Transient visual disturbances (blurred vision)
• Chest pain
• Temporary loss of vision

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids.

Constipation:

Add fruits, vegetables whole grains, and other high-fiber foods to your normal diet.

Dizziness:

Get up and move around to feel awake, and take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat healthy food to boost energy.

WARNING & PRECAUTIONS

PREGNANCY

Stopnaus inj is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice.

BREASTFEEDING

Stopnaus inj is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

This medicine has no or negligible effect on the ability to drive or use machines.

LIVER

Stopnaus inj should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Tell if you are allergic (hypersensitive) to Ondansetron.

HEART DISEASE

Stopnaus inj should be used with caution in patients suffering from uneven heartbeat or any other active heart disease. Consult your doctor for advice.

OTHERS

Inform your doctor if you have or had,

• Blockage in your gut or suffer from severe constipation
• Surgery to the adenoids or tonsils
• Problems with the levels of salts in blood like potassium and magnesium

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• Apomorphine (used to treat Parkinson’s Disease)
• Phenytoin, carbamazepine (used to treat epilepsy)
• Rifampicin, erythromycin (an antibiotic)
• Tramadol (used to treat pain)
• Haloperidol, methadone
• Medicines used to treat heart problems such as abnormal heartbeats (antiarrhythmics)
• Fluoxetine, paroxetine, sertraline (used to treat depression)
• Anthracyclines
• Ketoconazole (used to treat fungal infection)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT Stopnaus inj

Can Stopnaus inj be given in children?

Your doctor will administer the right dose depending on your child’s age and body weight.

Can use Stopnaus inj during pregnancy?

It is not recommended in the first trimester of pregnancy unless necessary. Consult your doctor for advice.