METOLIZ-PG2

INTRODUCTION

Metoliz-PG2 Tablet is a combination medicine that helps control blood sugar levels. This medicine is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in proper utilisation of insulin, thereby lowering the blood sugar levels.

Metoliz-PG2 Tablet should be taken in the dose and duration as advised by your doctor. It must be taken with food to avoid stomach upset. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. Overdose may lead to low blood sugar (hypoglycemia).

Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol or upon skipping a meal. Monitor your blood sugar levels regularly while taking it. Other common side effects of this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and respiratory tract infection.

Before taking this medicine, inform your doctor if you have any kidney, liver or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

USES OF Metoliz-PG2 TABLET

• Treatment of Type 2 diabetes mellitus

BENEFITS OF Metoliz-PG2 TABLET

In Treatment of Type 2 diabetes mellitus

Metoliz-PG2 Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

SIDE EFFECTS OF Metoliz-PG2 TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metoliz-PG2

• Hypoglycemia (low blood glucose level)
• Dizziness
• Headache
• Nausea
• Vomiting
• Diarrhea
• Flatulence
• Bronchitis (inflammation of the airways)
• Anemia (low number of red blood cells)
• Edema (swelling)

HOW TO USE Metoliz-PG2 TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metoliz-PG2 Tablet is to be taken with food.

HOW Metoliz-PG2 TABLET WORKS

Metoliz-PG2 Tablet is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

SAFETY ADVICE

AlcoholUNSAFE

It is unsafe to consume alcohol with Metoliz-PG2 Tablet.

PregnancyCONSULT YOUR DOCTOR

Metoliz-PG2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feedingCONSULT YOUR DOCTOR

Metoliz-PG2 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

DrivingCAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

KidneyCAUTION

Metoliz-PG2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metoliz-PG2 Tablet may be needed. Please consult your doctor.

Use of Metoliz-PG2 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

LiverCAUTION

Metoliz-PG2 Tablet should be used with caution in patients with liver disease. Dose adjustment of Metoliz-PG2 Tablet may be needed. Please consult your doctor.

Use of Metoliz-PG2 Tablet is not recommended in patients with severe liver disease.

WHAT IF YOU FORGET TO TAKE Metoliz-PG2 TABLET?

If you miss a dose of Metoliz-PG2 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.