Crizine-25

INTRODUCTION

Crizine- 25MG contains Hydroxyzine which belongs to a group of medicines called antihistamines. It helps in relieving anxiety and tension, managing pruritus due to chronic urticaria and atopic and contact dermatoses and histamine-mediated pruritus.

Hydroxyzine has sedative and anxiolytic effects due to its high affinity for histaminic receptors in the brain. Due to its antihistaminic and sedative properties, it is also useful in pruritus and urticaria. Crizine- 25MG blocks the action of histamine in the body which is responsible for allergic symptoms and also decreases the activity in the brain and helps in relieving anxiety and tension.

Always take this Crizine- 25MG exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, pregnant and breastfeeding. Your doctor will prescribe the right dose depending on your child’s age and body weight. The common side effects are dry mouth, dizziness, constipation and headache.

USES OF Crizine- 25MG

• Symptomatic relief in atopic pruritus
• Management of anxiety (in adults)

HOW Crizine- 25MG WORKS

Crizine- 25MG is in a class of medications called antihistamines. It blocks the action of histamine in the body which is responsible for allergic symptoms and also decreases the activity in the brain and helps in relieving anxiety and tension.

DIRECTIONS FOR USE

Always take this Crizine- 25MG exactly as your doctor has told you. Swallow this medicine as a whole and do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF Crizine- 25MG

SERIOUS

• Swelling of the face, tongue or throat
• Difficulty in swallowing and breathing and hives 
• Blistering of the skin
• Tremor (shakiness) or convulsions (fits)

COMMON

• Dry mouth
• Constipation
• Dizziness
• Headache
• Confusion

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, darkroom.

Dry mouth:

Chew sugar-free gum or suck on sugar-free hard candies to stimulate the flow of saliva and limit your caffeine intake. Drink small sips of water regularly.

Dizziness:

Get up and move around to feel awake, and take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat healthy food to boost energy.

Constipation:

Add fruits, vegetable whole grains and other high-fibre foods to your normal diet.

WARNING & PRECAUTIONS

PREGNANCY

Crizine- 25MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

Crizine- 25MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or handle any machines while taking this medicine, since it may cause drowsiness or less alertness.

ALCOHOL

Consumption of alcohol is not recommended during treatment with Crizine- 25MG.

KIDNEY

Crizine- 25MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

Crizine- 25MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic (hypersensitive) to Hydroxyzine.

HEART DISEASE

Crizine- 25MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Inform your doctor if you have or had,

• Are an asthmatic who has suffered a bad reaction to an antihistamine in the past
• Porphyria (a disease which causes stomach pain, constipation, changes in the colour of urine, skin rashes and disturbing behaviour)
• Glaucoma (increased pressure in the eye)
• Difficulty passing urine (enlarged prostate)
• Digestive system or stomach problems
• Myasthenia gravis (a muscle weakness disorder)
• Dementia
• Seizure disorders 
• Breathing problems
• Bladder outflow obstruction
• Hyperthyroidism (overactive thyroid)

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

•  Adrenaline or epinephrine
• Barbiturates, benzodiazepines (for sleeping disorders and epilepsy)
• Cimetidine (for ulcers and heartburn)
• Anti-emetics (drugs effective against vomiting and nausea)
• Betahistine (used to treat Ménière’s disease)
• Anaesthetics
• Muscle relaxants
• Opioids (used to relieve severe pain)
• Anticholinergic medicines (used for irritability, bowel syndrome, asthma or incontinence)
• Aminophylline (for breathing problems)
• Benzylpenicillin salts and chloramphenicol sodium succinate
• Doxorubicin hydrochloride (used for cancer)
• Isocarboxazid or moclobemide, amitriptyline (used for depression)
• Medicines to treat anxiety, psychosis
• Edrophonium and neostigmine
• Atropine
• Antiepileptic medicines
• Other antihistamines

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT Crizine- 25MG

Does Crizine- 25MG make you sleepy?

This medicine blocks the effects of histamine in your body, which makes you sleepy.

How fast does Crizine- 25MG work for sleep?

It has its maximal effect about 30 to 60 minutes after it is taken and lasts for 4 to 6 hours.

Is Crizine- 25MG bad for your heart?

It has the potential to block hERG channels and other types of cardiac channels, resulting in a potential risk of QT interval prolongation and cardiac arrhythmia events. Consult your doctor before taking the medicine.